This is a list by Angela James of Carina Press. They are reasons why editors pass on manuscripts. Keep in mind, I just copied her bullets. To read the editors’ in depth responses, select the link. The list does make you stop and think, “Could this be a problem?”
1. The manuscript doesn’t catch the reader’s attention from the start.
2. The story doesn’t stand out as fresh or unique.
3. The author has included too many unimportant details and not enough important details
4. The writing just isn’t there
5. The voice of the manuscript/characters doesn’t work
6. The reader can’t connect to the characters, they’re not fully realized or believable
7. The story requires too much suspension of disbelief
8. The manuscript starts well but doesn’t follow through
9. Unnecessary subplots
10. The conflict wasn’t sustainable